|
|
Ala-Pro-7-amido-4-trifluoromethylcoumarin + H2O <=> Ala-Pro + 7-amino-4-trifluoromethylcoumarin
|
3.4.14.2
dipeptidyl-peptidase II
3.4.14.5
dipeptidyl-peptidase IV
3.4.21.B28
|
–
–
–
|
|
|
BRENDA:
BS364866
SABIO-RK:
13103
|
|
|
|
acetyl-QTGG-7-amido-4-trifluoromethylcoumarin + H2O <=> acetyl-QTGG + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.B71
3.4.22.B74
3.4.22.B75
|
–
–
–
|
|
|
BRENDA:
BS416498
|
|
|
|
benzyloxycarbonyl-L-Phe-L-Arg-7-amido-4-trifluoromethylcoumarin + H2O <=> Benzyloxycarbonyl-Phe-Arg + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.15
cathepsin L
3.4.22.B49
|
–
–
|
|
|
BRENDA:
BS414362
|
|
|
|
Val-Asp-Val-Ala-Asp-7-amido-4-trifluoromethylcoumarin + H2O <=> VDVAD + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.55
caspase-2
|
–
|
|
|
BRENDA:
BS415428
|
|
|
|
LEVD-7-amido-4-trifluoromethylcoumarin + H2O <=> LEVD + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.57
caspase-4
|
–
|
|
|
BRENDA:
BS431053
|
|
|
|
N-acetyl-Phe-Arg-7-amido-4-trifluoromethylcoumarin + H2O <=> Acetyl-Phe-Arg + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.15
cathepsin L
3.4.22.B49
|
–
–
|
|
|
BRENDA:
BS432184
|
|
|
|
N-acetyl-PEVD-7-amido-4-trifluoromethylcoumarin + H2O <=> acetyl-PEVD + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.60
caspase-7
|
–
|
|
|
BRENDA:
BS450350
|
|
|
|
Arg-7-amido-4-trifluoromethylcoumarin + H2O <=> L-arginine + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.16
cathepsin H
|
–
|
|
|
BRENDA:
BS449581
|
|
|
|
Ac-Leu-Glu-Thr-Asp-7-amido-4-trifluoromethylcoumarin + H2O <=> Ac-Leu-Glu-Thr-Asp + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.61
caspase-8
|
–
|
|
|
BRENDA:
BS449490
|
|
|
|
Ac-Arg-Arg-7-amido-4-trifluoromethylcoumarin + H2O <=> acetyl-Arg-Arg + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.1
cathepsin B
|
–
|
|
|
BRENDA:
BS449479
|
|
|
|
Boc-RERR-7-amido-4-trifluoromethyl_coumarin + H2O <=> Boc-RERR + 7-amino-4-trifluoromethylcoumarin
|
3.4.21.B24
|
–
|
|
|
BRENDA:
BS449703
|
|
|
|
Val-Glu-Ile-Asp-7-amido-4-trifluoromethylcoumarin + H2O <=> Val-Glu-Ile-Asp + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.59
caspase-6
|
–
|
|
|
BRENDA:
BS450798
|
|
|
|
Benzyloxycarbonyl-Gly-Arg_4-trifluoromethylcoumarin_7-amide + H2O <=> Benzyloxycarbonyl-Gly-Arg + 7-amino-4-trifluoromethylcoumarin
|
3.4.21.59
tryptase
|
–
|
|
|
BRENDA:
BS15362
|
|
|
|
acetyl-LEHD-7-amido-4-trifluoromethylcoumarin + H2O <=> acetyl-LEHD + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.62
caspase-9
|
–
|
|
|
BRENDA:
BS381333
|
|
|
|
Phe-Pro-7-amido-4-trifluoromethylcoumarin + H2O <=> Phe-Pro + 7-amino-4-trifluoromethylcoumarin
|
3.4.21.B28
|
–
|
|
|
BRENDA:
BS393202
|
|
|
|
Ile-Pro-7-amido-4-trifluoromethylcoumarin + H2O <=> Ile-Pro + 7-amino-4-trifluoromethylcoumarin
|
3.4.21.B28
|
–
|
|
|
BRENDA:
BS392246
|
|
|
|
Lys-Ala-7-amido-4-trifluoromethylcoumarin + H2O <=> Lys-Ala + 7-amino-4-trifluoromethylcoumarin
|
3.4.21.B28
|
–
|
|
|
BRENDA:
BS392500
|
|
|
|
acetyl-D-Ala-Pro-7-amido-4-trifluoromethylcoumarin + H2O <=> acetyl-D-Ala-Pro + 7-amino-4-trifluoromethylcoumarin
|
3.4.21.B28
|
–
|
|
|
BRENDA:
BS399865
|
|
|
|
D-Ala-Pro-7-amido-4-trifluoromethylcoumarin + H2O <=> D-Ala-Pro + 7-amino-4-trifluoromethylcoumarin
|
3.4.21.B28
|
–
|
|
|
BRENDA:
BS400737
|
|
|
|
N-benzyloxycarbonyl-L-Leu-L-Arg-7-amido-4-trifluoromethylcoumarin + H2O <=> benzyloxycarbonyl-Leu-Arg + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.52
calpain-1
|
–
|
|
|
BRENDA:
BS411843
|
|
|
|
N-acetyl-Asp-Glu-Val-Asp-7-amido-4-trifluoromethylcoumarin + H2O <=> acetyl-DEVD + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.41
cathepsin F
3.4.22.56
caspase-3
3.4.22.59
caspase-6
3.4.22.60
caspase-7
3.4.22.62
caspase-9
|
–
–
–
–
–
|
|
|
BRENDA:
BS404189
|
|
|
|
N-benzyloxycarbonyl-Gly-Gly-Arg-7-amido-4-trifluoromethylcoumarin + H2O <=> benzyloxycarbonyl-Gly-Gly-Arg + 7-amino-4-trifluoromethylcoumarin
|
3.4.21.73
u-plasminogen activator
|
–
|
|
|
BRENDA:
BS15594
|
|
|
|
Benzyloxycarbonyl-Lys-Arg_4-trifluoromethylcoumarin_7-amide + H2O <=> Benzyloxycarbonyl-Lys-Arg + 7-amino-4-trifluoromethylcoumarin
|
3.4.21.59
tryptase
|
–
|
|
|
BRENDA:
BS15363
|
|
|
|
Leu-7-amino-4-trilfluoromethylcoumarin + H2O <=> L-leucine + 7-amino-4-trifluoromethylcoumarin
|
3.4.11.1
leucyl aminopeptidase
|
–
|
|
|
BRENDA:
BS382136
|
|
|
|
Lys-Pro-4-trifluoromethylcoumarin-7-amide + H2O <=> Lys-Pro + 7-amino-4-trifluoromethylcoumarin
|
3.4.21.B28
|
–
|
|
|
BRENDA:
BS366409
|
|
|
|
DEVD-7-amido-4-trifluoromethylcoumarin + H2O <=> DEVD + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.56
caspase-3
|
–
|
|
|
BRENDA:
BS411975
|
|
|
|
Nalpha-carbobenzoxy-L-Arg-L-Arg-7-amido-4-trifluoromethylcoumarin + H2O <=> Benzyloxycarbonyl-Arg-Arg + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.1
cathepsin B
3.4.22.35
histolysain
|
–
–
|
|
|
BRENDA:
BS394570
|
|
|
|
Ac-IETD-fluoromethylcoumarin + H2O <=> Ac-IETD + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.63
caspase-10
|
–
|
|
|
BRENDA:
BS418424
|
|
|
|
Ac-IETD-fluoromethylcoumarin + H2O <=> acetyl-IETD-7 + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.61
caspase-8
|
–
|
|
|
BRENDA:
BS418871
|
|
|
|
Gly-Pro-7-amido-4-trifluoromethylcoumarin + H2O <=> glycine + L-proline + 7-amino-4-trifluoromethylcoumarin
|
3.4.13.9
Xaa-Pro dipeptidase
|
–
|
|
|
BRENDA:
BS36458
|
|
|
|
ubiquitin-7-amido-4-trifluoromethylcoumarin + H2O <=> ubiquitin + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.B50
|
–
|
|
|
BRENDA:
BS432450
|
|
|
|
N-benzyloxycarbonyl-FR-7-amido-4-trifluoromethylcoumarin + H2O <=> N-benzyloxycarbonyl-FR + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.B49
|
–
|
|
|
BRENDA:
BS450356
|
|
|
|
IETD-7-amido-4-trifluoromethylcoumarin + H2O <=> IETD + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.59
caspase-6
3.4.22.61
caspase-8
3.4.22.62
caspase-9
|
–
–
–
|
|
|
BRENDA:
BS361963
|
|
|
|
benzyloxycarbonyl-Gly-Pro-Arg-7-amido-4-trifluoromethylcoumarin <=> Benzyloxycarbonyl-Gly-Pro-Arg + 7-amino-4-trifluoromethylcoumarin
|
3.4.21.B6
|
–
|
|
|
BRENDA:
BS366554
|
|
|
|
Ac-DEVD-7-amino-4-trifluoromethyl_coumarin + H2O <=> 7-amino-4-trifluoromethylcoumarin + Ac-DEVD
|
3.4.22.55
caspase-2
|
–
|
|
|
BRENDA:
BS381307
|
|
|
|
DEVD-AFC + H2O <=> DEVD + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.55
caspase-2
|
–
|
|
|
BRENDA:
BS381788
|
|
|
|
L-Arg-7-amido-4-trifluoro-methylcoumarin + H2O <=> L-arginine + 7-amino-4-trifluoromethylcoumarin
|
3.4.11.1
leucyl aminopeptidase
|
–
|
|
|
BRENDA:
BS382106
|
|
|
|
VDVADAFC + H2O <=> VDVAD + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.55
caspase-2
|
–
|
|
|
BRENDA:
BS382955
|
|
|
|
Z-VDVAD-7-amino-4-trifluoromethyl_coumarin + H2O <=> 7-amino-4-trifluoromethylcoumarin + Z-VDVAD
|
3.4.22.55
caspase-2
|
–
|
|
|
BRENDA:
BS382984
|
|
|
|
VEID-7-amido-4-trifluoromethylcoumarin + H2O <=> VEID + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.59
caspase-6
|
–
|
|
|
BRENDA:
BS385909
|
|
|
|
acetyl-Ala-Glu-Val-Asp-4-trifluoromethylcoumarin-7-amide + H2O <=> acetyl-Ala-Glu-Val-Asp + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.63
caspase-10
|
–
|
|
|
BRENDA:
BS391127
|
|
|
|
acetyl-Leu-Leu-Tyr-7-amido-4-trifluoromethyl_coumarin + H2O <=> N-acetyl-LLY + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.53
calpain-2
|
–
|
|
|
BRENDA:
BS418876
|
|
|
|
acetyl-LSTT-7-amido-4-trifluoromethylcoumarin + H2O <=> acetyl-LSTT + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.29
picornain 2A
|
–
|
|
|
BRENDA:
BS391161
|
|
|
|
N-acetyl-Val-Glu-Ile-Asp-7-amido-4-trifluoromethylcoumarin + H2O <=> acetyl-VEID + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.59
caspase-6
|
–
|
|
|
BRENDA:
BS392743
|
|
|
|
N-acetyl-Val-Glu-Ile-Asp-7-amido-4-trifluoromethylcoumarin + H2O <=> Ac-VEID + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.59
caspase-6
|
–
|
|
|
BRENDA:
BS418437
|
|
|
|
D-Val-Leu-Arg-7-amido-4-trifluoromethylcoumarin + H2O <=> D-Val-Leu-Arg + 7-amino-4-trifluoromethylcoumarin
|
3.4.21.35
tissue kallikrein
3.4.21.B12
|
–
–
|
|
|
BRENDA:
BS362027
|
|
|
|
Gly-Pro-7-amido-4-trifluoromethylcoumarin + H2O <=> Gly-Pro + 7-amino-4-trifluoromethylcoumarin
|
3.4.14.5
dipeptidyl-peptidase IV
3.4.21.B28
|
–
–
|
|
|
BRENDA:
BS366410
|
|
|
|
Ac-Leu-Glu-Val-Asp-7-amido-4-trifluoro_methylcoumarin + H2O <=> 7-amino-4-trifluoromethylcoumarin + Ac-Leu-Glu-Val-Asp
|
3.4.22.57
caspase-4
|
–
|
|
|
BRENDA:
BS404167
|
|
|
|
Ac-LRGG-7-amido-4-trifluoromethylcoumarin + H2O <=> N-acetyl-Leu-Arg-Gly-Gly + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.B74
3.4.22.B75
|
–
–
|
|
|
BRENDA:
BS416497
|
|
|
|
Ac-Trp-Glu-His-Asp-7-amino-4-trifluoromethylcoumarin + H2O <=> acetyl-WEHD + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.36
caspase-1
|
–
|
|
|
BRENDA:
BS432189
|
|
|
|
acetyl-Ile-Glu(OMe)-Thr-Asp(OMe)-7-amido-4-trifluoromethylcoumarin + H2O <=> acetyl-Ile-Glu(OMe)-Thr-Asp(OMe) + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.61
caspase-8
|
–
|
|
|
BRENDA:
BS404200
|
|
|
|
L-Ala-7-amido-4-trifluoro-methylcoumarin + H2O <=> L-alanine + 7-amino-4-trifluoromethylcoumarin
|
3.4.11.1
leucyl aminopeptidase
|
–
|
|
|
BRENDA:
BS382097
|
|
|
|
L-Pro-L-Ala-7-amido-4-trifluoromethylcoumarin + H2O <=> Pro-Ala + 7-amino-4-trifluoromethylcoumarin
|
3.4.14.5
dipeptidyl-peptidase IV
|
–
|
|
|
BRENDA:
BS409716
|
|
|
|
benzyloxycarbonyl-IETD-7-amido-4-trifluoromethylcoumarin + H2O <=> benzyloxycarbonyl-IETD + 7-amino-4-trifluoromethylcoumarin
|
3.4.22.61
caspase-8
|
–
|
|
|
BRENDA:
BS411715
|
|